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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab7f2a4f41e0efe74dc10c44f5445727994b23624c393ec727df2e4aebd98016' 
  AND token = 'CubAiFXSG2OSH7512o//2qN+SwYglC2BF4EXVEZhYAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}