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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f180d14911e0139d7155670c813870a071742aab2862e2674d8e0ab335222256' 
  AND token = 'L24Che/3pXi6nit6baPhSqW0N1vx45TE0GmYhccL8o8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}