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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a73c4601093dd8e7524ecc5f74b8522b6a94ed54877745567c82319e8d567d38' 
  AND token = 'PJh4hzXiQESTvoZ8HV5FCuED+4j9Nbzozo5xByCzCX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}