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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4afe6f8e1361405f2af3ecbe951b4f48e26370c910f2ba167a60106d81d07a7f' 
  AND token = 'fhTxe0hCMXo1JjPKtk2m9zLHBksGv3fhOLpaAIk7Rrs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}