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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5b71bea8c1819a7142dba0cfb5db1a24ec1bad52e9c8161de95d2664e84fbab' 
  AND token = 'XrNpmnyQ1SJZcZNTd8aXRQL3s3EYISXfiuP5cSk0qN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}