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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '927becd1609f5258eaadf9848a6976fec19d67da00f1946c7a03584a6d35d575' 
  AND token = 'C5MAGF+UF7Wuh2Da20r1i35tw/KZUMwz7GFJUY4pv48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}