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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ae67abf18becce720e8a9307d531ba765c7dcfd53dacf4a31d658a9b8379db8' 
  AND token = 'sKPD9RQgzcUxrJ8r4tnLKeuNrcpWwnl1gogvEISEH0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}