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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '243b27f3e116303a633c9a863a87ffc57e2c10df6fd651a55529a43ef205338e' 
  AND token = 'chZdgSTxSDQn21TcsZnPIFc/loO/oIEhWMgnU71/9ss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}