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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7043c5ce181ac47537570c0cd8fcc73204f968aa50ed9973d32bfc8cd916150' 
  AND token = 'sI57n3s5CEoAwPaaDd0lZjENVcjMS2wlEucO+Y/PDtI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}