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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cbd7372b2c6f6ead0d870985494a0040b0fd26912ad7f17be39c50335c9ba24' 
  AND token = 'wE09ZpaEWHWk769XNmKP2+ZjHZG3hTJ5uOIN9wZdZI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}