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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3011c72143c1d1bb16ddfd726e81686d80b61720614c34212f35c2b7550afdc7' 
  AND token = 'Z7I/KGDmRxiomy+Ygpiz1x45TC4xBn36ynIVUxpmf+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}