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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd156c989f3b9ce720879e8c56b65697d8cdf83e410d91b1c3c9812ec4e9d044' 
  AND token = 'DZw6xEYn5uLvB4KfA2E3RyOyth7ShCuw4Tv+C2a7wHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}