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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1731da64ab81fed0f5c68e54de53dffb0376941561c23cbc69af7a545b488857' 
  AND token = 'QwRWQ24se1U0xIQN7V5CR4mSRkI7EOIlAmn1pXlxrHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}