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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b201517edeca5d1f5fcc4d493e113fe12366a554dccc7cbb4d3c094f8ce7347' 
  AND token = 'TymDovnl7MU0Bl2cN/p2HB8AJ285yAWaPuwJW2IvqxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}