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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c18947432186ae0e4254839d58c348268ef94f48d56d2f2236fbdc2156719091' 
  AND token = 'Y1GKsKLUDI2GB2cJKJn4WMWWkaJmMiI+RFcM7rqlVNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}