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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef0d9fa342eeb1181de51d06873d1cfd5eed74d827578ae51205cc58dc1d3dc6' 
  AND token = 'Kxl6XMG7DuTpTeIjINLQ4EqkcLpXvpLi33xKnh7LVvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}