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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbe68dcf93aa8603b601ce2f024b7346fba7dcafce3f38f1b913f3442612dc78' 
  AND token = 'Uo0eJsuDBlJyDGSPkvPwk2wk8uqfLyl8v9TBE8ArPrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}