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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d298df67769de5e1b3ab635de6a0c19c6667d83b12976f50542bb3a501016e1' 
  AND token = 't6QRMmpnDzhm5YWOfDK/bznLJCWG+jDUnkuz4nOWmx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}