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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1825cae58f12ddf84b8b04b8807704ebcabdb261e2c666fba9e0b4a3bf6b895' 
  AND token = 'm8luqoHgBznsvKJqBhenm7nn82Sr+mGhFEi2uAIGDqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}