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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '291dd7e65d2d6b8bea12636b042f5efbd079c0b653280bfff4b0b885bb4cc797' 
  AND token = '683XnLmLGYaf5jfkcwIa1zF5DKpDOxKA+3BJ5k5nG1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}