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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eff14410d2e6ef3b68d58a5e6e9fd8eb9747d8686a27c6e474420f650267fff3' 
  AND token = 'XFSyrQo4kRbkOleXTyBN2FmVKRM0UYnLstOKhHmVcbE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}