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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1075d8d98db4ac569dbb7a49fbc0a8c44884508e52f8555bcef3a277326ed2f' 
  AND token = 'PyNB286bg21aR1UcMnbC52jF/SR4atsWndzxYiQJcPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}