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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00eb620d9c67cd360db4b77ddad45de4a463c3595e5ed2932ac7b80fcec1c52f' 
  AND token = 'kxl/1Y6b//4SqjwFHA+bi3Sa7GVg/J3XB/iTN12sMSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}