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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce4b36b0ac89433c16a2e3a3938f29674106aafcac4788a6beb9ed15c81a83d5' 
  AND token = '4lsNOAfCgAXf3/EtRZ1kJh1DqkWKzf6pxmTjOFz1RlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}