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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0dedb86647c2ba18d00e828080a924ddfe5cbb2992839fbde801584013d9d56' 
  AND token = 'du+Y7v29+eiOfXCPoP4Y6u3STqI5G7cbgTY5xmIQk4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}