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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63d8d453dba02289559a98ee38f1b0d53165116338a48858cbf11284c02f651f' 
  AND token = 'ACWpTo9llm9+R6T++pWKFZR3brChvJ94meQF7IRHaik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}