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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1064b8b57ad26f12ebf0a34dab7aecb021a3a81ea3be5fc4ffdb39343f3e9529' 
  AND token = 'mofp4+oZCGKnAb7qh2igeNYXQIXU0QrHwnRRHxYcSfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}