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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '739cb49167274842eb85a872c38369162d2368d64d63a9960424a7fe07e2d1d5' 
  AND token = 'xGg+u2zoa8QgD4aIsXx1o0yeJDAAbJ+c56z8M2viixU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}