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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '219836da0d55a336923776e855a8483ed295d177fb96dcbeeb5d4ecaca93f7ea' 
  AND token = 'R+YLKUjxL/lKOaymA4xCvzkcc1iS5dE1XLot/3CuTmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}