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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cacf4e02eb3e6101a289d7d3c4cd186e7a766d5bc426ac1d00c459f4c1be3b67' 
  AND token = 'XHLuokySeUMBWva2AEYszs6zZJPI4vRk1BuvTTvrI/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}