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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4e54cb3784a9bc0cc7a30b96200179a410ef17638ab23ad3030a62816dc4f87' 
  AND token = 'gV61CrbdkVuooTVz0XSphbtdgiX+VQgGCcfp1se0AHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}