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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd927e1271fe21abf4fbd28d04c43846218b05e5da4617c55aa13ab0fffbd7f2' 
  AND token = 'rEl0uQde34u5i4HT1KCZ2RMF2sLY/t/LAPuTt5vHj9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}