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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2190bd66a5a5635a0f3b5fbc27a028b87c075f4ea6d68059be2ea5ae04213e2d' 
  AND token = 'DeQEyTdzHmyqzsCEd20WWbWTrNMvXhZvsfIjAWb0nR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}