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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e4ef3cd6319e4ac08f21d71108335cda9385f81a976236847652034cf9299a9' 
  AND token = 'Z04rFA7q/uPQosn2BGk73Dcp+NuHZ3CsYsYEZFacWnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}