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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a87b1e6d4db4d96e5253bd0814ef7904f6400569cc3e1cbf25013467965c941' 
  AND token = 'PPO669MOrE78SVbW7quYUNHiqtbQqYXvqWWfeef++AM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}