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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f54d7944c7208fcb0e2e832f774867902a950621ed30a02a3266aad13cb807be' 
  AND token = '5yQ15lGzQetj4Dlt233p+eo7dUl6eqSct9NENVsHc58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}