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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc8a13f4cb055d6f035924002a3c8394f73ad58ccb69603be9cbe8ff8c73daa2' 
  AND token = 'iq/uXDp+fI6PYcx0MngScUHNxg5n5mCG5+jpZN6Ux2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}