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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c80d0962272ab9895abe95f99a871a3a60775365f80ebd88cf71092e33edefe' 
  AND token = 'xwyllv1SDYa6BcH1wjuoAlNS1SZ5rfcposu+gvST1BE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}