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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6074824380d18a3f8eecc51e9649cee458891eaf1df632dce9ff0620a5f0794' 
  AND token = 'GSzI60X5f9Wtwk3TVlZTf1M2E56Kmy2e6/kTJDImtGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}