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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41624be9caf1e0618e71cd05a7b1791f20ef1c9e67ec9f8616094346deadc9c7' 
  AND token = 'xglCIN6fC9YqwVh6JwxeuBFR/Zs6tPIZRIqZTimjpF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}