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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d9a205d5c684cf2754c686b8fc4da5118acff84e111b397d5b637c8130454c6' 
  AND token = 'TxZbi/ltbBWARFn55n2m0Kw7CjFTcmSZfQK2/XiOmIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}