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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b2dec45d7a3ab8b901b9d52a134c959e304ecb3c67cba842c009b2d8be47d03' 
  AND token = 'mwUHdIEolmwvjA9hrAF8LbYxMW4X24yNGYmrH+YpIK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}