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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff2508e025eb3ed09cf53a65b9285aed50510549afad8fb777dac61afc4cec68' 
  AND token = 'mvTz5PoZ9nkzws54UQSOgzz7RevfgqhxFOSAI6r2oBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}