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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38307a1d09c88c965f4e480e6b618805a82aed646c29ec819b3bceca7d779788' 
  AND token = 's66AfeOcFQ3Sq8SF3yOM5k09zlEd6EUZRwVxb03FPj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}