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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a6678a4d6f5c498946ebcbc97eac4d8f4d8728f0d24f24fd26b9786263f8a25' 
  AND token = 'lIr1HBn/Nc87Ae4F5knmh0aFZugRjtsj41H7TpgD05A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}