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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '357d75685bdea2438a2d91ad36af435a0079d5ea61d686a181dc2bd7a7a6986c' 
  AND token = 'PX4B30U4zwiSphUWF8ODkWCMHBUBZZGTines4g7l3BA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}