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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd72cdbd691758ae4217c4e891822b733c11a11e1af71b4b1e23778859aa68b59' 
  AND token = '4SIssd5z7f1TmjTd0ZaK+22X1RRymD5QR/7+BfY5JC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}