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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a90b11cb2e2063130e58d5e6b16e577c8bf707f67035b3e829649ad07ed05885' 
  AND token = 'UU44MLsIsAeqkHEPKxp2q+LVB6MVOWMnERsCkzrqOA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}