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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5738536e41bc7781b8a4ed3f8c2d661d0ae3e425fd994082fa6261550c4edb72' 
  AND token = 'ySY3+bRJzt3l2VWQJsvKZiw6pz8FFt15cRvvlbotjdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}