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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74db46580d2ff9452a1df6efb1b88c98e4bd20ff5840cc32b9afd48d57d29e03' 
  AND token = '/EbbUqaEkrDrBXVbzx2xDwYi1vqwzoe3FwWypYbdiXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}